A kind of by suffering or just suffer to prevent or the method for the tissue injury that treatment is correlated with ischemia-reperfusion injury and thoracoabdominal aortic aneurysm (TAAA) repairing with complement inhibitor that patient that ischemia-reperfusion injury or thoracoabdominal aortic aneurysm (TAAA) are repaired relevant tissue injury uses tissue injurys preventive dose or therapeutic dose to one.Described complement inhibitor is preferably the antibody that is bonded to and suppresses to participate in the complement protein of MAC formation, is preferably the antibody that suppresses MBL, MASP1, MASP2 and MASP3 in the lectin pathway.Described complement inhibitor can be used singly or in combination to reduce by repairing the M ﹠ M that relevant tissue injury causes with ischemia-reperfusion injury or TAAA.
