The invention relates to systems and methods for delivering highly focused photodisruptive laser pulses with pulse durations <;50 picoseconds into the anterior chamber angle region of an eye, creating channels into various anatomical structures within the anterior angle of the eye and thereby facilitating aqueous outflow for the treatment of Glaucoma. The invention includes novel gonioscopy lens systems, patient interface systems and laser delivery systems to deliver such focused laser beams to the anterior angle area and other areas of the eye.