Darryl Wayne Hilliard,Junliang Hao,David Andrew Coates
申请号:
US16386684
公开号:
US20190322639A1
申请日:
2019.04.17
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The invention provides certain (phenyl)-(pyrazol)-3,4-dihydroisoquinolin-2(1H)-yl)ethan-1-one compounds of formula I as D1 positive allosteric modulators (PAMs), and pharmaceutical compositions thereof. The invention further provides methods of using a compound of formula I, or a pharmaceutically acceptable salt thereof, to treat certain symptoms of Parkinson's disease, schizophrenia, ADHD or Alzheimer's disease.