Gang An,S. Mark OHara,David Ralph,Robert W. Veltri
申请号:
US13328565
公开号:
US20120213789A1
申请日:
2011.12.16
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention concerns preventative, therapeutic, and diagnostic methods and compositions involving UC markers, such as UC 28, for cancer. It includes methods and compositions for targeting cancer cells using a differentiation agent in combination with a therapeutic agent targeted to cells that differentially express a UC marker after exposure to the differentiation agent. The invention also includes methods of inducing immune responses against UC markers, as well as antibodies that recognize UC markers, which may be employed for therapeutic and diagnostic methods.