An imaging system of microbubble therapy cooperated with an ultrasound device for monitoring a cavitation on microbubbles in a vessel of an affected part is disclosed in the present invention, in which the cavitation is occurred by applying an ultrasound to disrupt the microbubbles. The system comprises an image acquiring module and a controlling module. The image acquiring module comprises at least one magnetic resonance device for acquiring a plurality of magnetic resonance images of the cavitation, and the controlling module provided for controlling an acquiring time of the magnetic resonance device and an irradiation time of the ultrasonic device through a controlling mode. An image evaluation method using the same is also disclosed herein and comprises steps as the following. First, injecting the microbubbles into the vessel of the affected part is performed. And then, a plurality of magnetic resonance images by a magnetic resonance device and in an acquiring time is acquired. The microbubbles are irradiated for an irradiation time by an ultrasound. Finally, changes of the magnetic resonance images will be monitored, in which an irradiation path of the ultrasound may be perpendicular to a direction of flow in the vessel and the irradiation time is within the acquiring time.
