#$%^&*AU2018274888A120181220.pdf#####C: Interwovn NRPortbl DCC AAR 18129860 _.doc-5 12 2018 ABSTRACT OF THE DISCLOSURE The invention provides improved T cell compositions and methods for manufacturing T cells. More particularly, the invention provides methods of T cell manufacturing that result in adoptive T cell immunotherapies with improved survival, expansion, and persistence in vivo.