Disclosed herein are systems, devices, and methods for orthopedic surgical guides adapted to the anatomy of a patient and configured to align a bone shaping device or acetabular implant in a predetermined orientation. Certain embodiments constitute alignment guides for conducting hip surgery on a specific patient. Such guides include a first or inner surface structured to fit in a predetermined configuration relative to a portion of a patients anatomy based on topography data of the patients anatomy, a receiving surface configured to receive or constrain a bone shaping device or acetabular implant, and a reference surface with an alignment site that directs placement of the orthopedic device in a predetermined orientation relative to the patients anatomy when the first surface is in the predetermined configuration.
