A film with an alginate layer and a manufacturing method thereof are provided. The method utilizes a thin-layer carrier capable of absorbing liquid, in which the carrier is in a form of non-woven fabric, woven-fabric, a porous spongy film, a film, etc. that is formed by at least one synthetic or natural fiber or polymer and utilizes at least two separate but sequentially proceeded coating procedures for respectively coating a layer of an alginate aqueous solution containing an appropriate weight percentage (wt%) of sodium alginate or potassium alginate and a layer of salt compound aqueous solution containing an appropriate weight percentage of divalent metal ions, such as calcium ions, uniformly on at least one surface of the thin-layer carrier, so as to allow the alginate and the divalent metal ions of the salt compound to perform crosslinking for forming a hydrogel-type complex compound layer on the surface of the thin-layer carrier including on a top of the surface or deeper in an internal layer of the surface. Thereby, the film with the alginate (such as calcium alginate) layer and the thin-layer carrier can be continuously, rapidly, and massively produced. Wherein, when the surface of the thin-layer carrier is a rough surface, the formed alginate layer is integrated with the thin-layer carrier when the surface of the thin-layer carrier is a smooth surface, the formed alginate layer is easy to be separated from the thin-layer carrier, such that an application scope of the film is improved.
