This disclosure relates to systems and methods that use contextual information relating to a user's emotions and/or moods in connection with information targeting and content tagging. In some embodiments, user moods and/or emotional states may be determined and/or otherwise inferred using certain contextual information collected using one or more sensors included in devices associated with a user. Obtaining information relating to a user's mood and/or emotional state may allow for, among other things, more efficient targeting of content, search results, and/or other information that is well matched to a user's interests at a given point in time. In further embodiments, information relating to a user's mood and/or emotional state may be used to tag and/or otherwise associate content with information relating to the user's mood and/or emotional state while viewing and/or capturing the content.