NAVIDEA BIOPHARMACEUTICALS, INC.;OHIO STATE INNOVATION FOUNDATION
发明人:
COPE, Frederick,BLUE, Michael,METZ, Wendy,SCHLESINGER, Larry
申请号:
HK16113910.2
公开号:
HK1225623A
申请日:
2016.12.06
申请国别(地区):
HK
年份:
2017
代理人:
摘要:
A method of diagnosing a CD206 expressing cell-related disorder by administering a pharmaceutical composition to a subject, the composition including a carrier molecule having a detectable moiety attached thereto. The carrier molecule has a dextran backbone, and at least one receptor substrate conjugated, directly or indirectly, to the dextran backbone, wherein the receptor substrate is chosen so as to specifically bind to CD206. A method of treating a CD206 expressing cell-related disorder is also provided, as well as an ex vivo method and kit for quantitating the number of cells expressing CD206 in a bodily fluid.