ISOTHIAZOLO-PYRIMIDINEDIONE DERIVATIVES AS TRPA1 MODULATORS

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专利权人:

GLENMARK PHARMACEUTICALS S.A.

发明人:

KUMAR SUKEERTHI,KUMAR Sukeerthi,THOMAS ABRAHAM,THOMAS Abraham,MARGAL SANJAY,MARGAL Sanjay,KHAIRATKAR-JOSHI NEELIMA,KHAIRATKAR-JOSHI Neelima,MUKHOPADHYAY INDRANIL,MUKHOPADHYAY Indranil

申请号：

SI201030232

公开号：

SI2411397T1

申请日:

2010.03.22

申请国别(地区):

SI

年份:

2013

代理人:

摘要：

The present invention is related to novel isothiazolo[3,4-d]pyrimidinedione and isothiazolo[5,4-d]pyrimidinedione derivatives as TRPA (Transient Receptor Potential subfamily A) modulators. In particular, compounds described herein are useful for treating or preventing diseases, conditions and/or disorders modulated by TRPA1 (Transient Receptor Potential subfamily A, member 1). Also provided herein are processes for preparing compounds described herein, intermediates used in their synthesis, pharmaceutical compositions thereof, and methods for treating or preventing diseases, conditions and/or disorders modulated by TRPA1.

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