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MNK INHIBITORS AND METHODS RELATED THERETO
专利权人:
发明人:
Siegfried H. Reich,Paul A. Sprengeler,Stephen E. Webber,Alan X. Xiang,Justin T. Ernst
申请号:
US15809011
公开号:
US20180085368A1
申请日:
2017.11.10
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention relates to compounds according to Formula (I):or a stereoisomer, tautomer or pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4a, R4b, R5, R6, R7, R8, W1, W2, Y and n are as defined herein. Also described are pharmaceutically acceptable compositions of Formula I compounds as well as methods for utilizing the compounds of Formula I and the pharmaceutically acceptable compositions of Formula I compounds as inhibitors of Mnk as well as therapeutics for the treatment of diseases such as cancer.
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