The medicine active ingredient relatively abundantly is included offers the grain condition formulation which can show satisfactory grain property and the like in spite. As for this invention, being the grain condition formulation which consists of the inorganic material which is allowed pharmacy and the grain which includes the medicine active ingredient, (1) the aforementioned inorganic material is water poor solubility, it relates to the grain condition formulation where (2) content of the aforementioned medicine active ingredient is, 50 - 95 weight % features thing.医薬有効成分が比較的多量に含まれているにもかかわらず、良好な粒子特性等を発揮できる粒子状製剤を提供する。本発明は、薬学的に許容される無機材料及び医薬有効成分を含む粒子からなる粒子状製剤であって、(1)前記無機材料が水難溶性であり、(2)前記医薬有効成分の含有量が50~95重量%である、ことを特徴とする粒子状製剤に係る。
