Disclosed are methods and apparatuses for treating a pregnancy related hypertensive disorder, such as pre-eclampsia and eclampsia, using ex vivo treatment with an anti-sFlt-1 receptor (sFlt-1) antibody bound to a solid support in order to reduce blood levels of sFlt-1. Further disclosed are the sequences of the heavy chain and light chain CDRs of the anti-sFlt-1 antibodies.固体支持体に結合した抗sFlt-1受容体(sFlt-1)抗体を用いたエクスビボ治療をsFlt-1の血中レベルを低下させるために使用して、子癇前症および子癇等の妊娠関連高血圧性障害を治療するための方法および装置を開示する。