#$%^&*AU2020101112A420200730.pdf#####ABSTRACT The present invention provides a carborane-modified mesoporous silica nanosphere (MSN) and a preparation method thereof, and belongs to the technical field of nanomaterial. The present invention first covalently links carborane to the surface of mesoporous silica, and the preparation method thereof features easy operation and low equipment requirement. Meanwhile, nanoparticles prepared thereby feature structural stability, controllable hydrophilicity and hydrophobicity, and high boron content； the modified material is not toxic to organisms, can be applied to drug loading systems, and further has a potential for using as a boron-containing reagent in boron neutron capture therapy of tumors.3/6 HEt2O ~Li NVHn-C 4H9Li -- ~FIG. 3
