Kevin J. Tracey,Howland Shaw Warren,Christine N. Metz
申请号：
US12198808
公开号：
US08391970B2
申请日:
2008.08.26
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Described herein are methods, devices and systems for inhibition of granulocyte activation by appropriate stimulation of the vagus nerve. Methods of treating granulocyte-mediated disorders (including inflammatory disorders) by stimulating the vagus nerve to inhibit granulocyte activation (particularly neutrophil activation) are also described. Appropriate stimulation may be very low levels of stimulation, including stimulation that does not result in desensitization. The level of granulocyte activation may be detected and used to at least partially control stimulation.
