PFEIFER, ANDREA,PIHLGREN, MARIA,MUHS, ANDREAS,WATTS, RYAN
申请号：
HRP20090221
公开号：
HRP20090221B1
申请日:
2009.04.14
申请国别(地区):
HR
年份:
2015
代理人:
摘要：
The present invention is related to methods and compositions for the therapeutic and diagnostic use in the treatment of diseases and disorders which are caused by or associated with amyloid or amyloid-like proteins including amyloidosis, a group of disorders and abnormalities associated with amyloid protein such as Alzheimer's disease. The present invention provides novel methods and compositions comprising highly specific and highly effective antibodies having the ability to specifically recognize and bind to specific epitopes from a range of j3-amyloid proteins. The antibodies enabled by the teaching of the present invention are particularly useful for the treatment of diseases and disorders which are caused by or associated with amyloid or amyloid- like proteins including amyloidosis, a group of diseases and disorders associated with amyloid plaque formation including secondary amyloidosis and age-related amyloidosis including, but not limited to, neurological disorders such as Alzheimer's Disease (AD).Ovaj izum odnosi se na kimerno i humanizirano protutijelo, te na postupke i pripravke namijenjene upotrebi u terapiji i dijagnostici kod liječenja amiloidoze, koja je skupina poremećaja i nenormalnosti uzrokovanih amiloidnim proteinom, poput Alzheimerove bolesti.
