Solid oral composition comprises agomelatine or its hydrate, complexes, co-crystals, crystalline forms, addition salts with an acid or a base, and one or more excipients comprising diluents, binders, flowing agents, lubricants, coating agents, plasticizers, flavors, anti-irritants or sweeteners, where the composition has: an absolute bioavailability of greater than 25% and a bioavailability greater than that obtained for an orodispersible tablet with an oromucosal absorption containing the active principle agomelatine under the same form and at the same dosage.La invención tiene por objeto una composición farmacéutica bucal sólida que contiene agomelatina destinada a una acción sistémica.
