HOEKSTRA, WILLIAM J.,SCHOTZINGER, ROBERT J.,RAFFERTY, STEPHEN WILLIAM
申请号：
CA2837400
公开号：
CA2837400C
申请日:
2011.04.22
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
The instant invention describes compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes. The invention describes a compound of Formula (I), or salt thereof, wherein: (see formula I) MBG is optionally substituted tetrazolyl, optionally substituted triazolyl, or optionally. substituted pyrazolyl； R1 is halo； R2 is halo； each R3 is independently alkyl, cyano, haloalkyl, alkoxy, halo, haloalkoxy, R4 is aryl optionally substituted with 0, 1, 2 or 3 independent R3； R5 is H, or -C(O)alkyl optionally substituted with amino； n is 0, 1, 2 or 3.
