Disclosed in the present invention is a use of E-10-hydroxyl-2-decylenic acid in preparation of medicine or a health care product for preventing and treating osteoporosis. Active ingredient in the medicine or the health care product is only E-10-hydroxyl-2-decylenic acid, wherein the E-10-hydroxyl-2-decylenic acid is artificially synthesized or extracted from royal jelly. In the present invention, a novel use of E-10-hydroxyl-2-decylenic acid is disclosed for the first time. Experiment results prove that E-10-hydroxyl-2-decylenic acid has the obvious prevention and treatment effect on the osteoporosis, so that E-10-hydroxyl-2-decylenic acid can be used to the preparation of medicine or the health care product for preventing and treating osteoporosis. In addition, E-10-hydroxyl-2-decylenic acid is stable； can be simply prepared with low cost, and has homology of medicine and food. When E-10-hydroxyl-2-decylenic acid is used to prepare the medicine or the health care product for preventing and treating osteoporosis, it has the advantages of low cost, good prevention and treatment effect, low consumption, no toxic and side effects after long-time administration and the like. Moreover, wide application prospects are expected in the field of medicine or the health care product.La présente invention concerne l'utilisation de l'acide E-10-hydroxyle-2-décylénique dans la préparation d'un médicament ou d'un produit de soins de santé pour prévenir et traiter l'ostéoporose. L'ingrédient actif dans le médicament ou le produit de soins de santé est uniquement l'acide E-10-hydroxyle-2-décylénique, l'acide E-10-hydroxyle-2-décylénique étant artificiellement synthétisé ou extrait de la gelée royale. Dans la présente invention, une nouvelle utilisation de l'acide E-10-hydroxyle-2-décylénique est décrite pour la première fois. Les résultats d'expérience prouvent que l'acide E-10-hydroxyle-2-décylénique présente l'effet de prévention et de traitement évident sur l'ostéoporose, de sort
