苯並氮雜䓬磺酰胺化合物

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专利权人:

F. Hoffmann-La Roche AG;豪夫邁．羅氏有限公司

发明人:

HOVES, Sabine,KOERNER, Matthias,WANG, Lisha,YUN, Hongying,ZHU, Wei,ZHANG, Weixing

申请号：

HK18103012.8

公开号：

HK1243701A

申请日:

2018.03.02

申请国别(地区):

HK

年份:

2018

代理人:

摘要：

This invention relates to novel benzazepine sulfonamide compounds of the formula (I), wherein R4 or R5 is -SO2-NR7R8 and R1 to R8 and Y are as defined in the description and in the claims, as well as pharmaceutically acceptable salts thereof. These compounds are TLR agonists and may therefore be useful as medicaments for the treatment of diseases such as cancer, autoimmune diseases, inflammation, sepsis, allergy, asthma, graft rejection, graft-versus-host disease, immunodeficiencies, and infectious diseases.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/