Meir Shinitzky,Irun R. Cohen,Raanan Margalit,Yaacov Herzig,Jeffrey Sterling,Gyorgy Toth,Istvan Miskolczi,Ferenc Rantal,Tivadar Tamas
申请号:
US10530776
公开号:
US08987263B2
申请日:
2003.10.09
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Basic esters of fatty alcohols of the general formula: R1-O—CO-A or pharmaceutically acceptable salts thereof, wherein R1 is C12-C24 alkyl or C10-C24 alkenyl, and A is a residue containing at least one acyclic or cyclic amino group and/or at least one heteroaromatic ring containing a tertiary or quaternary nitrogen atom, are anti-inflammatory and immunomodulatory agents, useful in the treatment of immunologically-mediated inflammation, as adjuvants for antigens involved in both cellular and humoral responses.