An endovascular prosthetic system comprises an prosthetic device (10) witha major lumen extending therethrough, a major wall, at least one opening (16,19, 31) in the major wall; at least one branch (18, 20, 40) extending into the majorlumen of the prosthetic device (10) the or each branch having a minor lumen, a minorwall, and a fenestration (15) in the minor wall in communication with the majorlumen; and at least one guide wire (17) extending through the fenestration andout of the prosthesis through the opening.