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Morphinan derivative and medical usage thereof
专利权人:
University of Tsukuba
发明人:
Nagase, Hiroshi,Yamamoto, Naoshi,Irukayama, Yoko,Saitoh, Tsuyoshi,Yanagisawa, Masashi,Nagumo, Yasuyuki
申请号:
AU2016346558
公开号:
AU2016346558A1
申请日:
2016.10.28
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
The purpose of the present invention is to provide a compound that is effective as a prophylactic agent or a therapeutic agent for various diseases and symptoms associated with the orexin receptor, as well as to provide a medical usage thereof. The present invention provides a morphinan derivative that is represented by general formula (I), that exhibits superior selectivity and antagonism with respect to the orexin receptor, and that exhibits superior therapeutic and prophylactic effects with respect to drug dependency, or provides a pharmacologically acceptable acid-addition salt thereof, as well as an orexin-receptor antagonist and a drug-dependency therapeutic agent or prophylactic agent, that contain the morphinan derivative or the acid-addition salt as an active ingredient.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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