An endotracheal tube assembly comprises an elongate tube having an outer wall defining an outer surface, the tube defining an elongate central lumen and an elongate suction lumen, and an inflatable cuff attached on a distal end portion of the elongate tube. The elongate tube defines a first suction opening having a normal vector parallel to a tangent to an outer circumference of a transverse cross-section of the outer wall of the tube next to said first suction opening, the first suction opening being in fluid communication with the suction lumen.