Cardiopolymers;Henry Ford Health System; Inc.;Cardiopolymers, Inc.;The Regents of the University of California
发明人:
Hinson, Andrew G.,Sabbah, Hani N.,Lee, Randall J.
申请号：
AU2007293055
公开号：
AU2007293055B2
申请日:
2007.09.07
申请国别(地区):
AU
年份:
2013
代理人:
摘要：
Cardiomyopathy may be treated by distributing space-occupying agent withinthe myocardium in a pattern about one or more chambers of the heart, such that thespace-modifying agent integrates into and thickens at least part of the cardiacwall about the chamber so as globally to reduce wall stress and stabilize or evenreduce chamber size. Some patterns also cause a beneficial global reshapingof the chamber. These changes occur quickly and are sustainable, and have a rapidand sustainable therapeutic effect on cardiac function. Over time the reliefof wall stress reduces oxygen consumption and promotes healing. Moreover, variouslong-term therapeutic effects may be realized depending on the properties ofthe space-occupying agent, including combinations.with other therapeuticmaterials. Specific cardiac conditions treatable by these systems and methodsinclude, for example, dilated cardiomyopathy (with or without overt aneurismalformations), congestive heart failure, and ventricular arrhythmias, myocardialinfarctions, and mitral regurgitation.
