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Substituted 1,4,10-triazadibenzo[cd,f]azulenes, substituted 1,4,5,10-tetraazadibenzo[cd,f]azulenes and substituted 1,4,5,7,10-pentaazadibenzo[cd,f]azulenes as bromodomain inhibitors
专利权人:
AbbVie Inc.
发明人:
Steven D. Fidanze,Dauchun Liu,Robert A. Mantei,Keith F. McDaniel,John Pratt,George S. Sheppard,Le Wang,Andrew Bogdan,James H. Holms,Justin D. Dietrich,Jasmina Marjanovic,Lisa A. Hasvold,Yujia Dai
申请号:
US14774866
公开号:
US10035800B2
申请日:
2014.03.12
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention provides for compounds of formula (I) wherein R1, R2, R6, Y1, Y3, A1, A2, A3 and A4 have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions, including inflammatory diseases, cancer, and AIDS. Also provided are pharmaceutical compositions comprising one or more compounds of formula (I).
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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