Provided is a lymphatic vessel stabilizer composed of Tie2 activator. The Tie2 activator is preferably at least one type selected from the group consisting of angiopoietin 1 (Ang-1), extract of Cinnamomum species plants, extract of Siberian Ginseng and syringaresinol.本發明提供一種包含Tie2活化劑之淋巴管之安定化劑。Tie2活化劑較好的是選自由血管生成素1(Ang-1)、肉桂(Cinnamomum)屬植物之萃取物、西伯利亞人蔘(Siberian Ginseng)萃取物及紫丁香樹脂酚(Syringaresinol)所組成群中之至少1種。