Tel HaShomer Medical Research Infrastructure and Services Ltd.
发明人:
Benjamin DEKEL,Orit HARARI-STEINBERG
申请号:
US15320847
公开号:
US20170199195A1
申请日:
2015.06.25
申请国别(地区):
US
年份:
2017
代理人:
摘要:
A method of identifying cancer stem cell markers in a human primary tumor is disclosed. The method comprises:(a) in vivo passaging the primary tumor; and(b) comparing a level of at least one antigen in a first population of passaged tumor cells of the primary tumor with a second population of tumor cells of the primary tumor,wherein an increase in the amount of the antigen in the first population of tumor cells as compared to the amount of the antigen in the second population of tumor cells is indicative of a cancer stem cell marker in the human primary tumor.