연세대학교 원주산학협력단;YONSEI UNIVERSITY WONJU INDUSTRY-ACADEMIC COOPERATION FOUNDATION
发明人:
KIM, KYUNG HWAN,김경환,RYU, SANG BAEK,류상백,CHANG, JIN WOO,장진우,BAE, EUN KYUNG,배은경,SHIN, HYUNG CHUEL,신형철,KIM, JIN HYUNG,김진형,IM, CHANG KYUN,임창균
申请号：
KR1020120042558
公开号：
KR1020130119620A
申请日:
2012.04.24
申请国别(地区):
KR
年份:
2013
代理人:
摘要：
The present invention relates to an apparatus for closed-loop electrical brain stimulation using neural response signals. The apparatus for closed-loop electrical brain stimulation using neural response signals according to the present invention comprises one or more neural signal measuring units which measure neural signals generated by neural activities of brain, and an artifact removal unit which detects a single neural signal and local brain potential signals by removing the electrical stimulation artifact from neural signals including electrical stimulation artifact caused by initial electrical stimulation. Also, the present invention comprises a neural signal analysis unit which determines suitability of initial electrical stimulation by comparing quantitative changes in a single neural signal and local brain potential signals before and after initial electrical stimulation is added and analyzing the quantitative changes and initial electrical stimulation added to the brain. In addition, the present invention comprises an electrical stimulation parameter control unit which determines parameters of second electrical stimulation which will be added according to suitable determination； an electrical stimulation production unit which produces stimulation pulse of second electrical stimulation added to the brain； current source for adding second electrical stimulation to the brain； and an electrical stimulation unit equipped with stimulation electrodes. Furthermore, the present invention comprises a neural signal recording unit which records neural signals measured in the neural signal measuring units. [Reference numerals] (101) Neural signal measuring unit；(102) Artifact removal unit；(103) Neural signal analysis unit；(104) Electrical stimulation parameter control unit；(105) Electrical stimulation production unit；(106) Electrical stimulation unit；(107) Neural signal recording unit；(AA) Brain본 발명은 뇌 조직에 전기자극을 가하는 뇌 전기자극 장치에 관한 것으로, 본 발명에 따른 뇌신경신호반응 기반의 폐루프형 뇌 전기자극 장
