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COMPOSÉ AYANT UNE ACTIVITÉ DE CONTRACTION MUSCULAIRE DU DETRUSOR ET UNE ACTIVITÉ DE RELAXATION MUSCULAIRE DU SPHINCTER URÉTRAL
专利权人:
LTD.;ONO PHARMACEUTICAL CO.
发明人:
申请号:
EP10786192.4
公开号:
EP2441760B1
申请日:
2010.06.09
申请国别(地区):
EP
年份:
2013
代理人:
摘要:
Since a compound represented by formula (I) wherein all of the symbols are the same as defined in the specification, a salt thereof, a solvate thereof, a prodrug thereof, a mixture with a diastereomer thereof in an arbitrary ratio, or a cyclodextrin clathrate thereof have a contracting activity of bladder detrusor and a relaxing activity of urethral sphincter, they can ameliorate bladder contraction dysfunction and/or urethral relaxation dysfunction, and for example, are effective for underactive bladder. Additionally, the compound of the present invention has little risk of side effects on the urinary system, the circulatory system and the digestive system, and exhibits excellent pharmacokinetics, such as oral absorbability etc . Therefore, the compound of the present invention is useful as a superior agent for preventing, treating and/or ameliorating underactive bladder.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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