This invention concerns soft calcifediol capsules, their use in the treatment or prevention of diseases caused by vitamin D deficiency, such as vitamin D deficiency, demineralisation, such as hypocalcaemia and hypophosphataemia, renal osteodystrophy, rahitism, osteoporosis, osteopenia, osteoarthritis, osteoarthritis, osteoarthritis, osteomalacia, hypoparathyroidism and inflammatory bowel disease and their manufacturing process.Prezenta invenţie se referă la capsule moi de calcifediol, la utilizarea lor în tratamentul sau prevenirea bolilor cauzate de carenţa vitaminei D, cum ar fi carenţa vitaminei D, demineralizarea, precum hipocalcemia şi hipofosfatemia, osteodistrofia renală, rahitismul, osteoporoza, osteopenia, osteoartrita, osteoartroza, osteomalacia, hipoparatiroidismul şi boala inflamatorie a intestinului şi la un procedeu de fabricaţie a acestora.