COMPOSITIONS AND THEIR USE IN THE TREATMENT OF NEOPLASIA, INFLAMMATORY DISEASE AND OTHER DISORDERS

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专利权人:

DANA-FARBER CANCER INSTITUTE; INC.

发明人:

BRADNER, JAMES, ELLIOTT,QI, JUN

申请号：

DK11781422

公开号：

DK2571503T3

申请日:

2011.05.16

申请国别(地区):

DK

年份:

2015

代理人:

摘要：

The invention features compositions for treating or preventing a neoplasia. More specifically, the invention provides thienotriazolodiazepine compounds for disrupting the interaction of a BET family polypeptide comprising a bromodomain with chromatin (e.g., disrupting a bromodomain interaction with an acetyl-lysine modification present on a histone N-terminal tail).

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/