ZHOU, Yunlong,CAI, Suixiong,WANG, Guangfeng,JIAO, Lingling,MIN, Ping,JING, Yu,GUO, Ming
申请号：
EP15887309
公开号：
EP3287456A4
申请日:
2015.12.14
申请国别(地区):
EP
年份:
2018
代理人:
摘要：
Disclosed are a compound of the following formula (I) or a pharmaceutically acceptable salt thereof, a preparation method thereof, pharmaceutical compositions and uses thereof in the preparation of a medicine for inhibiting HIF prolyl hydroxylase or a medicine for promoting the generation of endogenous EPO, wherein in the formula (I), R 1 and R 2 are each independently hydrogen； R 3 is hydrogen or C 1-3 alkyl； and Ar is an aromatic ring or an heteroaromatic ring selected from a naphthalene ring, a pyridine ring, a thiophene ring, a furan ring and a substituted benzene ring.
