NEDERLANDSE ORGANISATIE VOOR TOEGEPAST - NATUURWETENSCHAPPELIJK ONDERZOEK TNO
发明人:
NIEUWENHUIZEN, WILLEM FERDINAND,HAVEKES, ALOYSIUS MARIA,EMEIS, JOSEPHUS JAN
申请号：
AT05813546
公开号：
AT539741T
申请日:
2005.11.25
申请国别(地区):
AT
年份:
2012
代理人:
摘要：
The present invention relates to the use of sphingolipids for the preparation of a food item, a food supplement and/or a medicament for the prevention and/or treatment of elevated blood levels of cholesterol and triglycerides related to steatosis and hepatotoxic effects of medicaments and viral infections. In particular, the invention relates to the use of a sphingolipid such as phytosphingosine, sphingosine, sphinganine, ceramide, glycosylceramide and/or sphingomyelin, or a precursor or a derivative of a sphingolipid, or a pharmaceutically acceptable salt thereof, for the prevention and/or treatment of hepatotoxic effects such as hepatic steatosis, fibrosis and/or cirrhosis.
