WADDELL, SHERMAN T.,BALKOVEC, JAMES M.,KEVIN, NANCY J.,GU, XIN
申请号:
CA2625871
公开号:
CA2625871C
申请日:
2006.10.16
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
Triazole derivatives of structural formula I are selective inhibitors of the11.beta.-hydroxysteroid dehydrogenase-1. The compounds are useful for thetreatment of diabetes, such as noninsulin-dependent diabetes (NIDDM),hyperglycemia, obesity, insulin resistance, dyslipidemia, hyperlipidemia,hypertension, Metabolic Syndrome, and other symptoms associated with NIDDM.