YONSEI UNIVERSITY WONJU INDUSTRY-ACADEMIC COOPERATION FOUNDATION
发明人:
KIM, TACK JOONG,김택중,SONG, MIN CHEOL,송민철
申请号：
KR1020110070124
公开号：
KR1020130009206A
申请日:
2011.07.14
申请国别(地区):
KR
年份:
2013
代理人:
摘要：
PURPOSE: A composition for suppressing vascular smooth muscle cell proliferation and a composition for preventing or treating cardiovascular diseases containing diethylstilbestrol are provided to prevent or treat cardiovascular diseases.CONSTITUTION: A pharmaceutical composition for suppressing smooth muscle cell proliferation contains a compound of chemical formula 1 as an active ingredient. The compound of chemical formula 1 is diethylstilbestrol. The concentration of the compound is 1-10 um. The pharmaceutical composition is used in an oral formulation including powders, granules, tablets, capsules, suspensions, emulsions, syrups, or aerosols. The pharmaceutical composition is an external use formulation, a suppository, and a sterilization injection solution. A health functional food and a pharmaceutical composition for suppressing smooth muscular cells contain the compound as an active ingredient. A pharmaceutical composition for preventing and treating arteriosclerosis, atherosclerosis, or restenosis contains the compound as an active ingredient.COPYRIGHT KIPO 2013본 발명은 디에틸스틸베스트롤(Diethylstilbestrol)을 유효성분으로 포함하는 혈관평활근세포 증식 억제용 조성물 및 심혈관 질환의 예방 또는 치료용 조성물에 관한 것이다. 본 발명의 디에틸스틸베스트롤은 대동맥 혈관평활근세포 증식 억제 활성을 가지고 있어서 심혈관 질환의 치료 또는 예방에 매우 유용하게 사용될 수 있다.
