Mutations of histone proteins associated with proliferative disorders

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专利权人:

发明人:

Nada Jabado,Stefan M. Pfister,Christoph Plass,Andrey Korshunov,Hendrik Witt,Dominik Sturm,David Jones,Peter Lichter,Elke Pfaff

申请号：

US14359900

公开号：

US09494591B2

申请日:

2012.11.21

申请国别(地区):

US

年份:

2016

代理人:

摘要：

The present application shows the relationship between variations in the amino acid sequence of histone proteins, more specifically the H3.3 protein, and proliferation-associated disorders. Herewith provided are predictive methods, commercial packages, therapeutic methods and screening methods based on this relationship.

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