PROBLEM TO BE SOLVED: To provide a guide wire which can curve at a desired position when reaching an occluded lesion and suppress the occurrence of a blood vessel perforation.SOLUTION: A guide wire 1 comprises: a long flexible wire main body 10； and a coil 4 which is formed by winding wires 411, 421, 431 spirally, and which is disposed at an outer periphery of a distal part of the wire main body 10 to cover the distal part. The coil 4 includes: a coil distal portion 41 disposed on a tip side of the distal part； a coil base end portion 42 disposed in a base end side of the coil distal portion 41； and a coil intermediate portion 43 which is disposed between the coil distal portion 41 and the coil base end portion 42, and includes the wire 431 having a wire diameter smaller than a wire diameter of the wires 411, 421 of the coil distal portion 41 and the coil base end portion 42.SELECTED DRAWING: Figure 2【課題】閉塞病変に到達した際に所望の位置で湾曲し、血管穿孔が生ずることを抑えることができるガイドワイヤを提供すること。【解決手段】ガイドワイヤ１は、可撓性を有する長尺のワイヤ本体１０と、素線４１１、４２１、４３１が螺旋状に巻回されて形成されたコイル４であってワイヤ本体１０の先端部の外周に配置され先端部を覆うコイル４と、を備える。コイル４は、先端部における先端側に配置されたコイル先端部４１と、コイル先端部４１よりも基端側に配置されたコイル基端部４２と、コイル先端部４１とコイル基端部４２との間に配置され、コイル先端部４１およびコイル基端部４２の素線４１１、４２１の線径よりも細い線径の素線４３１を有するコイル中間部４３と、を有する。【選択図】図２
