PEPTIDES FVIII POUR L'INDUCTION DE TOLÉRANCE IMMUNITAIRE ET IMMUNODIAGNOSTICS

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专利权人:

Baxalta Incorporated;Baxalta GmbH

发明人:

申请号：

EP17167928.5

公开号：

EP3260132A1

申请日:

2011.10.27

申请国别(地区):

EP

年份:

2017

代理人:

摘要：

The present invention is related to peptides that can be used to reduce the immune response against FVIII or to induce tolerance to human FVIII in patients with, e. g., hemophilia A. Furthermore, the peptides can be used for immunodiagnostic purposes to detect FVIII-specific CD4+ T cells to monitor patients with hemophilia A during replacement therapy and during immune tolerance induction therapy.

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