PROBLEM TO BE SOLVED: To provide a safe useful substance excellent in stability which sufficiently and sustainably functions in normalization of the motor system and prevention/recovery/amelioration of hypofunction, as well as prevention/recovery/amelioration of skin sagging, elasticity, wrinkles and pigmentation and normalization of keratin in a cosmetic system, and to provide applications and means thereof.SOLUTION: Provided are a cartilaginous precursor cell proliferation promoter, a cartilage differentiation promoter, a cartilage calcification inhibitor, a knee joint ameliorating agent, a skin sagging ameliorating agent, a skin elastic ameliorating agent, an ameliorating agent for skin wrinkles, a skin keratin ameliorating agent, a skin pigmentation inhibitor and a humectant, in which three kinds of molecular binding units obtained by binding, in the order of a certain sequence, five sugars including sulfate group or phosphate group partially and at a specific position are present at a terminal site in the molecule, as a main active molecular part, and whose active ingredient is a high molecular sugar chain compound obtained by hydrolyzing a glycoprotein substance extracted from cartilage tissues. Provided are also a health food, a health drink, a pharmaceutical composition or a cosmetic composition comprising these agents.SELECTED DRAWING: NoneCOPYRIGHT: (C)2016,JPO&INPIT【課題】運動器系の正常化,機能低下予防・回復・改善と、美容系における皮膚のたるみ,弾力,しわ,色素沈着の予防・回復・改善、角質の正常化に、十分且つ持続的に機能する安全で安定性良好な有用物質とその用途手段を提供する。【解決手段】主要な活性分子部分として、部分的かつ特定位に硫酸基またはリン酸基を含む5つの糖が一定の配列順で結合した3種類の分子結合単位が分子内の末端部位に存在する、軟骨組織より抽出された糖蛋白質物質を加水分解することによって得られる高分子糖鎖化合物を有効成分とする、軟骨前駆細胞増殖促進剤,軟骨分化促進剤,軟骨石灰化抑制剤,ひざ関節改善剤、皮膚たるみ改善剤,皮膚弾力改善剤,皮膚しわ改善剤,皮膚角質改善剤,皮膚色素沈着抑制剤,保湿剤と、それらを配合した健康食品,健康飲料,医薬品組成物,又は化粧料組成物。【選択図】なし
