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Method of producing heparan sulfate having anticoagulant activity
专利权人:
AJINOMOTO CO.; INC.
发明人:
Yuriko Tokura
申请号:
US16018269
公开号:
US10704068B2
申请日:
2018.06.26
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present invention provides a method of producing a heparan sulfate having an anticoagulant activity. Specifically, the present invention provides the method of producing a heparan sulfate having a desired molecular weight, by partially N-deacetylating a heparosan followed by depolymerizing the heparosan by heparinase III, and converting the produced low molecular weight product into heparan sulfate having an anticoagulant activity.
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