Dennis Liotta,Edgars Jecs,Robert James Wilson,Huy Hoang Nguyen,Michelle Bora Kim,Lawrence Wilson,Eric James Miller,Yesim Altas Tahirovic,Valarie Truax,Thomas Kaiser
申请号:
US16487825
公开号:
US20200054623A1
申请日:
2018.02.21
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The disclosure relates to chemokine CXCR4 receptor modulators and uses related thereto. The receptor modulators can be formulated to form pharmaceutical compositions comprising the disclosed compounds or pharmaceutically acceptable salts or prodrugs thereof. The compositions may be used for managing CXCR4 related conditions, typically prevention or treatment of viral infections abnormal cellular proliferation, retinal degeneration, inflammatory diseases, or as an immunostimulant or immunosuppressant or for managing cancer and may be administered with another active ingredient such as an antiviral agent or chemotherapeutic agent.