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Method of treating cancer with an HLA-A*3303-restricted WT1 peptide and pharmaceutical composition comprising the same
专利权人:
Inc.;International Institute of Cancer Immunology
发明人:
Haruo Sugiyama
申请号:
US14145221
公开号:
US08933038B2
申请日:
2013.12.31
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Disclosed are: a peptide comprising an amino acid sequence composed of contiguous nine amino acid residues derived from a WT1 protein, wherein an amino acid residue at position 2 in the amino acid sequence is selected from the group consisting of Ala, Ile, Leu, Val, Phe, Tyr, Ser and Asp and an amino acid residue at position 9 in the amino acid sequence is Arg; a polynucleotide encoding the peptide; a pharmaceutical composition comprising the peptide; and a method of treating cancer using the peptide.
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