A medical signal processing device receives an image signal in accordance with a result of examining inside of a subject and processes the image signal that includes a plurality of pixel data groups of respective pixels arrayed at a constant interval among pixels sequentially arrayed in a predetermined direction in an image made of pixels arrayed in a matrix. The pixel data groups are data of respective pixels that are different from each other, and the pixel data groups are input in the medical signal processing device in parallel. The medical signal processing device includes a distribution processing unit configured to generate a plurality of distributed image signals by combining, among the pixel data groups, pixel data groups of respective pixels that are separate from each other, and the distributed image signals are transmitted to an external medical control device through a plurality of respective signal transmission paths.