Russell P. Rother,Camille Bedrosian,Stephen P. Squinto,Leonard Bell
申请号：
US15243290
公开号：
US09771418B2
申请日:
2016.08.22
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present disclosure relates to, inter alia, compositions containing an inhibitor of human complement and use of the compositions in methods for treating or preventing complement-associated disorders. In some embodiments, the inhibitor is chronically administered to patients. In some embodiments, the inhibitor is administered to a patient in an amount and with a frequency to maintain systemic complement inhibition and prevent breakthrough. In some embodiments, the compositions contain an antibody, or antigen-binding fragment thereof, that binds to a human complement component C5 protein or a fragment of the protein such as C5a or C5b.
