THE CHILDREN'S HOSPITAL OF PHILADELPHIA;TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
发明人:
THOMAS-TIKHONENKO, ANDREI,CHUNG, ELAINE,PSATHAS, JAMES
申请号:
CA2872311
公开号:
CA2872311A1
申请日:
2013.05.01
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
Compositions and method for inhibiting, treating, and/or preventing a B-cell neoplasm are provided. In accordance with the present invention, methods of inhibiting, treating, and/or preventing cancer in a subject are provided. In certain embodiments, the methods comprise administering to the subject a therapeutically effective amount of at least one inhibitor of the CD19-PI3K interaction. In a particular embodiment, the method further comprises the administration of at least one other anti-cancer measure, such as the administration of at least one other chemotherapeutic agent and/or administration of radiation therapy.