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2,4-DIAMINOQUINAZOLINES FOR SPINAL MUSCULAR ATROPHY
专利权人:
FAMILIES OF SPINAL MUSCULAR ATROPHY
发明人:
SINGH, JASBIR,GURNEY, MARK E
申请号:
NZ57519807
公开号:
NZ575198A
申请日:
2007.08.01
申请国别(地区):
NZ
年份:
2012
代理人:
摘要:
Disclosed herein is a 2,4-diaminoquinazoline compound of formula (III), wherein Q is -CH2-, R1 is selected from the group consisting of aryl, substituted aryl, heteroaryl and substituted heteroaryl with the proviso that the compound is not 5-[1-(3,4-dichlorobenzyl)-piperidin-4-ylmethoxy]-quinazoline-2,4-diamine, processes for its preparation, compositions comprising said compounds, and uses thereof. Said compounds are useful for treating spinal muscular atrophy (SMA).
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