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PHARMACEUTICAL COMPOSITION COMPRISING PEGYLATED FAB' FRAGMENT OF ANTI-HUMAN NGF ANTIBODY
专利权人:
Astellas Pharma Inc.
发明人:
Ayano YAMAMOTO,Akinori CHIKUSHI
申请号:
US16087908
公开号:
US20200299371A1
申请日:
2017.03.24
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Provided is a stable pharmaceutical composition comprising a PEGylated Fab′; fragment of an anti-human NGF antibody, capable of inhibiting the formation of degradation products, multimers, acidic related substances, basic related substances, and insoluble foreign substances. The pharmaceutical composition has a pH of 4 to 5.5, and can further comprise a pharmaceutically acceptable buffer, a pharmaceutically acceptable isotonizing agent, and a pharmaceutically acceptable surfactant, if desired.
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