DANIEL JAMES FORD,HELEN TRACEY HORSLEY,JAMES THOMAS REUBERSON
申请号：
BR112018006135
公开号：
BR112018006135A2
申请日:
2016.09.28
申请国别(地区):
BR
年份:
2018
代理人:
摘要：
A series of substituted pyrazolos [1 of formula (I) as defined herein, 5 a] pyrimidine and pyrazolo [1,5 a] [1,3,5] pyrrolotriazine derivatives are the selective depressants of phosphatidylinositols 4 kinases III β (PI4KIII β) activity, it is beneficial in the treatment and/or prevention of a variety of human diseases, the disease includes inflammation sexual dysfunction, autoimmune disorders and oncology obstacle;Viral disease and malaria;With organ and cell transplant rejection.
